Replica Human Skull - Porotic Hyperostosis and Cribra Orbitalia

Porotic hyperostosis and cribra orbitalia are porous cranial lesions that are associated with metabolic or general nutritional stress. It is said to be caused by iron deficiency anemia, nutrient deficiencies, infectious disease, and/or poor sanitation. However, recent studies have suggested that hemolytic and megaloblastic anemias are the more likely cause of porotic hyperostosis. Porotic hyperostosis occurs as porous areas on the skull vault, while cribra orbitalia refers to porous areas within the orbits. This skull exhibits porotic hyperostosis involving posterior portion of the frontal bone, across the coronal suture into the left parietal bone. A small quarter-sized defect can be seen on the right parietal bone. Cribra orbitalia can be seen on the roof of the left eye orbit.

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